The Mytest One Step Troponin I Test device is a rapid visual immunoassay for the qualitative presumptive detection of cardiac Troponin I in human whole blood, serum, or plasma specimens
This kit is intended to be used as an aid in the diagnosis of myocardial infarction (MI); commonly known as a heart attack
Specifications: ◦ Detects cardiac troponin I(cTnI) as low as Conc. 0.25ng/ml ◦ For Serum/plasma/whole blood specimen ◦ Result in 15 minutes ◦ No cross reactivity
Kit contains: ◦ Mytest Troponin I test device individually foil pouched with a desiccant ◦ Assay Buffer ◦ Sample Applicator (Optional) ◦ Package insert
Troponin I is a cardiac and skeletal muscle protein useful in the laboratory diagnosis of heart attack. It occurs in different plasma concentration but the same circumstances as troponin T - either test can be performed for confirmation of cardiac muscle damage and laboratories usually offer one test or the other.
The level of troponin that indicates a heart attack is the level above the reference range. Cardiac troponin levels are normally so low they cannot be detected with most blood tests. Having normal troponin levels 12 hours after chest pain has started means a heart attack is unlikely. A normal value range may vary slightly among different laboratories.
Troponin is attached to the protein tropomyosin and lies within the groove between actin filaments in muscle tissue. In a relaxed muscle, tropomyosin blocks the attachment site for the myosin crossbridge, thus preventing contraction.